Hi !
Hivemail is in php and Mailyoulike is in asp and dotnet
Mailyoulike like have almost all the features which hivemail offers and some unique features which only mailyoulike offers
Hivemail requires a php_imap.dll to be enabled on your server in order to work ( most servers do not have that but they enable that on request and some don,t ) but for mailyoulike you do not need any component just upload the scripts and you have the system .
asp and dot net is microsoft and php is not 
If you plan to run your website on unix or lunix server then purchase Hivemail and if you plan to run your website on Windows servers then you can purchase any , that depends which one you like . and what are your requirments .
Thanks
Suhail kaleem
mailyoulike.com